Tomoko Makabe — Endo Lab

article 2016

Drospirenone reduces inflammatory cytokines, vascular endothelial growth factor (VEGF) and nerve growth factor (NGF) expression in human endometriotic stromal cells

Journal of reproductive immunology ·doi:10.1016/j.jri.2016.12.002

Drospirenone has been used as a progestin in oral contraceptives with ethinyl estradiol (DRSP/EE) and is expected to regulate endometriosis, however, the direct effects of drospirenone on endometriosis have not been clarified. The aim of th…

article 2016

Effects of 1,25-Dihydroxy Vitamin D3 on Endometriosis

The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2016-1515

CONTEXT: Endometriosis is an estrogen-dependent, chronic inflammatory disease. Recent studies have shown that vitamin D (VD) is an effective modulator of the immune system and plays an important role in controlling many inflammatory disease…

article 2016

Expressions of Ninjurin-1 in endometriosis and adenomyosis

·doi:10.1016/j.jri.2016.04.073

article 2016

Expressions of Ninjurin-1 in endometriosis and adenomyosis

·doi:10.1016/j.jri.2016.04.241

article 2016

ISP-32-5 Anti-inflammatory effects of drospirenone on endometriosis(Group 32 Endometriosis/Endometrium,International Session Poster)

article 2016

Resveratrol Enhances Apoptosis in Endometriotic Stromal Cells

American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12489

PROBLEM: Resistance to apoptosis, together with inflammatory and invasive activity, contributes to the pathogenesis of endometriosis; therefore, approaches that can safely enhance apoptosis in endometriotic tissue are highly sought after as…

article 2015

Drospirenone induces decidualization in human eutopic endometrial stromal cells and reduces DNA synthesis of human endometriotic stromal cells

Fertility and sterility ·doi:10.1016/j.fertnstert.2015.03.023

ObjectiveTo investigate the in vitro effect of drospirenone on human eutopic endometrial (EuSC) and ectopic endometriotic stromal cells (EcSC).DesignComparative and laboratory study. The experimental procedures were approved by the Institut…

article 2014

The serum level of vitamin D of endometriosis patients

·doi:10.1016/j.jri.2014.09.050