Whitfield B. Growdon

lab-animal 2024

Sialyl-Tn serves as a potential therapeutic target for ovarian cancer

Journal of ovarian research ·doi:10.1186/s13048-024-01397-1

BACKGROUND: Ovarian cancer remains the deadliest of the gynecologic cancers in the United States. There have been limited advances in treatment strategies that have seen marked increases in overall survival. Thus, it is essential to continu…

observational 2019

Recurrence, death, and secondary malignancy after ovarian conservation for young women with early-stage low-grade endometrial cancer

Gynecologic Oncology ·doi:10.1016/j.ygyno.2019.08.007

OBJECTIVE: To examine the association between ovarian conservation and oncologic outcome in surgically-treated young women with early-stage, low-grade endometrial cancer. METHODS: This multicenter retrospective study examined women aged <5…

2016

Next-generation genomic signature highlights sustained AKT and estrogen receptor signaling as key mediators of resistance following phosphatidylinositol 3-kinase (PI3K) inhibition in patient-derived xenograft models with and without PIK3CA gene mutations

·doi:10.1016/j.ygyno.2016.04.383

observational 2014

Endometriosis-associated ovarian malignancy: a retrospective analysis of presentation, treatment, and outcome

The Journal of reproductive medicine

OBJECTIVE: To investigate the relationship of age and tumors associated with endometriosis and outcome of different histologies of epithelial ovarian cancer arising from endometriosis. STUDY DESIGN: We identified cases of epithelial ovaria…