Takakura M

OBJECTIVE: Dienogest (DNG), a fourth-generation progestin, reduces pain associated with endometriosis and uterine adenomyosis; however, it is associated with irregular uterine bleeding that can cause anemia and poor quality of life. We inve…

Dienogest (DNG) is considered to be effective against ovarian endometrioma (OMA). We report a rare case of OMA transformation to ovarian cancer during long-term endometriosis treatment with a periodic administration of a gonadotropin-releas…

ObjectiveTo investigate the impact of estrogen contained in oral contraceptives (OCs) on the action of progestin on ovarian endometrioma epithelial cells.DesignExperimental in vitro study and immunohistochemical analysis.SettingUniversity h…

BACKGROUND: Epithelial cells of endometriotic tissues are difficult to propagate in vitro as experimental material is scarce owing to their limited life span. However, there is an increasing concern regarding their malignant transformation …

BackgroundSevere hemothorax is a rare complication after laparoscopic surgery for endometriosis, and the causes and proper management are not well understood.CaseWe report here the extremely rare case with massive hemothorax after laparosco…