Jeffrey D. Bray

No ORCID on file · 6 papers in corpus · active 2007-2012

Study types

  • other 3
  • article 2
  • book-chapter 1

Condition tags

  • endometriosis 6
other 2012
Activated glucocorticoid and eicosanoid pathways in endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.03.030

OBJECTIVE: To define altered gene expression networks in endometriosis. DESIGN: Experiments using endometriotic tissues and primary cells. SETTING: Division of Reproductive Biology Research, Northwestern University. PATIENT(S): Premenopa…

book-chapter 2011
Prostaglandin Pathway and Cortisol Metabolism Alterations in Endometriosis
·doi:10.1210/endo-meetings.2011.part3.p25.p3-180
other 2010
Improving the developability profile of pyrrolidine progesterone receptor partial agonists
Bioorganic & medicinal chemistry letters ·doi:10.1016/j.bmcl.2009.10.092

The previously reported pyrrolidine class of progesterone receptor partial agonists demonstrated excellent potency but suffered from serious liabilities including hERG blockade and high volume of distribution in the rat. The basic pyrrolidi…

article 2009
Estrogen-induced stromal cell-derived factor-1 (SDF-1/Cxcl12) expression is repressed by progesterone and by Selective Estrogen Receptor Modulators via estrogen receptor α in rat uterine cells and tissues
Steroids ·doi:10.1016/j.steroids.2009.07.011
other 2007
A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2006-0524

Selective progesterone receptor modulators (SPRMs) have been suggested as therapeutic agents for treatment of gynecological disorders. One such SPRM, asoprisnil, was recently in clinical trials for treatment of uterine fibroids and endometr…

article 2007
Noninvasive assessment of ectopic uterine tissue development in rats using magnetic resonance imaging
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.164