Maeda S

No ORCID on file · 3 papers in corpus · active 2012-2023
2023
Genetic insights into ossification of the posterior longitudinal ligament of the spine.
eLife ·doi:10.7554/elife.86514

Ossification of the posterior longitudinal ligament of the spine (OPLL) is an intractable disease leading to severe neurological deficits. Its etiology and pathogenesis are primarily unknown. The relationship between OPLL and comorbidities,…

2017
c-Jun N-terminal kinase in pancreatic tumor stroma augments tumor development in mice.
Cancer science ·doi:10.1111/cas.13382

Pancreatic ductal adenocarcinoma (PDAC) is a life-threatening disease and there is an urgent need to develop improved therapeutic approaches. The role of c-Jun N-terminal kinase (JNK) in PDAC stroma is not well defined even though dense des…

2012
CDX1 confers intestinal phenotype on gastric epithelial cells via induction of stemness-associated reprogramming factors SALL4 and KLF5.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1208651109

Intestinal metaplasia of the stomach, a mucosal change characterized by the conversion of gastric epithelium into an intestinal phenotype, is a precancerous lesion from which intestinal-type gastric adenocarcinoma arises. Chronic infection …