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The pathology of endometriosis is associated with various inflammatory cytokines, including IL-1β, and recent studies have shown that spheroid cell cultures can be used to investigate the mechanisms of endometriosis-associated inflammation …
PROBLEM: Endometriosis is a proliferative disease characterized by cytokine-induced inflammation. The objective of this study was to assess cell growth and PGE2 production induced by TNF-α in endometriotic stromal cells (ESCs) in spheroid c…
BackgroundUnlike many North American and European countries, Japan has observed a continuous increase in cancer incidence over the last few decades. We examined the most recent trends in population-based cancer incidence and mortality in Ja…
ObjectivesLow-dose estrogen-progestin (LEP) agents are often used for relieving endometriosis-associated chronic pelvic pain, but a direct effect of LEP on endometriotic lesions remains to be demonstrated. The objective of this study is to …
We describe a 47-year-old woman with severe aplastic anemia with genital bleeding who developed acute severe hepatitis after the administration of danazol while she was receiving cyclosporin. She had been diagnosed with severe aplastic anem…
A 48-year-old female was found to have right flank pain at another hospital and transabdominal ultrasonography showed right hydronephrosis. She was referred to our department for further examination. She had undergone right oophorectomy and…