Masataka Majima

Endometriosis is highly dependent on angiogenesis and lymphangiogenesis. Prostaglandin E2, an arachidonic acid metabolite, has been shown to promote the formation of new blood and lymphatic vessels. However, the role of another arachidonic …

Lymphatic vessels have crucial roles in the regulation of interstitial fluids, immune surveillance, and the absorption of dietary fat in the intestine. Lymphatic function is also closely related to the pathogenesis of various disease states…

Angiogenesis and lymphangiogenesis contribute to the development of endometriosis. We recently reported that thromboxane A2 (TXA2) receptor signaling involves in angiogenesis in critical limb ischemia and lymphangiogenesis in inflamed diaph…

Abstract Neuroimmune interactions are involved in the development of endometriosis. Here, we examined the role of a neuropeptide, calcitonin gene–related peptide (CGRP), and its receptor, receptor activity–modifying protein (RAMP) 1, in gro…

Lymphangiogenesis is related to the growth of endometriosis. Here, we examined whether vascular endothelial growth factor (VEGF) receptor 1 (VEGFR1) signaling plays a role in lymphangiogenesis during endometriosis. Endometrial fragments fro…

Newly formation of blood and lymphatic vessels is involved in the development of endometriosis. We have demonstrated that calcitonin gene-related peptide (CGRP) promotes wound healing and wound-associated formation of blood and lymphatic ve…

Lymphangiogenesis is associated with the growth of endometriosis. In this study, we examined the role of vascular endothelial growth factor (VEGF) receptor 1 (VEGFR1) signaling in lymphangiogenesis and tissue growth in an endometriosis mode…

Abstract Angiogenesis is critical in maintenance of endometrial tissues. Here, we examined the role of VEGF receptor 1 (VEGFR1) signaling in angiogenesis and tissue growth in an endometriosis model. Endometrial fragments were implanted into…