Jolande A. Land

No ORCID on file · 9 papers in corpus
other 2019
Combining individual Chlamydia trachomatis IgG antibodies MOMP, TARP, CPAF, OMP2, and HSP60 for tubal factor infertility prediction
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13091

PROBLEM: Tubal factor infertility (TFI) is a severe complication of genital Chlamydia trachomatis infections. In fertility workup, chlamydia antibody test (CAT) is used to predict TFI. The predictive value for TFI of most commonly used CAT …

diagnostic-accuracy 2019
Predictive Values of Serum Chlamydia trachomatis TroA and HtrA IgG Antibodies as Markers of Persistent Infection in the Detection of Pelvic Adhesions and Tubal Occlusion
Microorganisms ·doi:10.3390/microorganisms7100391

Chlamydia trachomatis IgG antibody testing (CAT) has been used as a screening test for tubal factor infertility (TFI), but as the CAT is only a marker of a past exposure to C. trachomatis and not of late sequelae, the positive predictive va…

observational 2016
TLR2, TLR4 and TLR9 genotypes and haplotypes in the susceptibility to and clinical course of Chlamydia trachomatis infections in Dutch women
Pathogens and disease ·doi:10.1093/femspd/ftv107

Chlamydia trachomatis infections demonstrate remarkable differences in clinical course that are approximately 40% based on host genetic variation. Here, we study the single nucleotide polymorphisms (SNPs) and their haplotypes in TLR2, TLR4 …

other 2012
Interruption of CXCL13-CXCR5 axis increases upper genital tract pathology and activation of NKT cells following chlamydial genital infection
PloS one ·doi:10.1371/journal.pone.0047487

BACKGROUND: Regulation of immune responses is critical for controlling inflammation and disruption of this process can lead to tissue damage. We reported that CXCL13 was induced in fallopian tube tissue following C. trachomatis infection. H…

other 2011
Pathogenesis: Development of the Female Genital Tract
·doi:10.1002/9781444398519.ch4

Sexual differentiation is governed by the presence or absence of testis-determining factor located on the Y chromosome. In an embryo in which testis-determining factor is expressed, the undifferentiated gonads will develop into testes, prod…

rct 2010
The LIFESTYLE study: costs and effects of a structured lifestyle program in overweight and obese subfertile women to reduce the need for fertility treatment and improve reproductive outcome. A randomised controlled trial
BMC women's health ·doi:10.1186/1472-6874-10-22

BACKGROUND: In the Netherlands, 30% of subfertile women are overweight or obese, and at present there is no agreement on fertility care for them. Data from observational and small intervention studies suggest that reduction of weight will i…

observational 2006
Do host genetic traits in the bacterial sensing system play a role in the development of Chlamydia trachomatis-associated tubal pathology in subfertile women?
BMC infectious diseases ·doi:10.1186/1471-2334-6-122

BACKGROUND: In women, Chlamydia (C.) trachomatis upper genital tract infection can cause distal tubal damage and occlusion, increasing the risk of tubal factor subfertility and ectopic pregnancy. Variations, like single nucleotide polymorph…

observational 2005
The CD14 functional gene polymorphism -260 C>T is not involved in either the susceptibility to Chlamydia trachomatis infection or the development of tubal pathology
BMC infectious diseases ·doi:10.1186/1471-2334-5-114

BACKGROUND: The functional polymorphism -260 C>T in the LPS sensing TLR4 co-receptor CD14 gene enhances the transcriptional activity and results in a higher CD14 receptor density. Individuals carrying the T/T genotype also have significantl…

lab-animal 1991
Lack of effect of peritoneal endometriosis on fertility in the rabbit model
Fertility and sterility ·doi:10.1016/s0015-0282(16)54496-3

STUDY OBJECTIVE: To study the isolated influence of peritoneal endometrial implants on fertility in an adhesion-free rabbit model. STUDY DESIGN: Thirty-two rabbits with endometrium implants were used; 31 rabbits with fat implants served as…