Rui Chen

ORCID: 0000-0002-7708-3962 · 13 papers in corpus
lab-animal 2026
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.76327

Endometriosis is a common gynecological disorder characterized by the ectopic growth of endometrium-like tissue outside the uterine cavity and is associated with pelvic pain, infertility, and reduced quality of life. Although several theori…

other 2025
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2025.02.048

STUDY OBJECTIVE: According to a four-level scale of endometriosis surgical complexity, the 2021 American Association of Gynecologic Laparoscopists (AAGL) endometriosis classification system was externally and prospectively validated. And we…

lab-animal 2024
Nutrients ·doi:10.3390/nu16183085

Melatonin, as an endocrine neurotransmitter, can promote the development of the ovary. Meanwhile, it also has protective effect on the ovary as an antioxidant. Thyroid hormone (TH) is essential for normal human reproductive function. Many s…

lab-animal 2023
Cell & bioscience ·doi:10.1186/s13578-023-01087-3

The two most prevalent subtypes of epithelial ovarian carcinoma (EOC) are ovarian clear cell carcinoma (OCCC) and high-grade serous ovarian carcinoma (HGSC). Patients with OCCC have a poor prognosis than those with HGSC due to chemoresistan…

other 2023
International journal of clinical practice ·doi:10.1155/2023/2291156

OBJECTIVE: Endometriosis, which is a common disease affecting approximately 10% of women of reproductive age, usually causes dysmenorrhea and infertility, thus seriously harming the patients' physical and mental health. However, there is a …

other 2022
BMC cancer ·doi:10.1186/s12885-022-10137-x

BACKGROUND: This study observed and described the morphological characteristics of the endometrium of the resected uterus using confocal laser endomicroscopy. This included benign endometrium, non-atypical endometrial hyperplasia, atypical …

observational 2022
Frontiers in genetics ·doi:10.3389/fgene.2022.969409

Purpose: To investigate the correlation between pre-ablation ultrasound radiomics features and the sonication energy for focused ultrasound surgery (FUS) of benign breast tumors. Method: 53 benign breast tumors of 28 patients treated by ult…

observational 2021
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590.2021.1928067

BACKGROUND: Endometriosis (EM) affects 10% women of reproductive age and alters fertility. Its management is still debated notably the timing of surgery and ART in infertility. Kallistatin (KS) is an endogenous protein that regulates differ…

observational 2021
·doi:10.21203/rs.3.rs-140378/v1

Abstract Background: Endometriosis (EM) affects 10% of women in reproductive age and alters fertility. Its management is still debated notably the timing of surgery and ART in infertility. Kallistatin (KS) is an endogenous protein that regu…

observational 2021
Journal of oncology ·doi:10.1155/2021/7548406

Cytochrome b reductase 1 (CYBRD1) promotes the development of ovarian serous cystadenocarcinoma (OV). We assessed the function of CYBRD1 in OV underlying The Cancer Genome Atlas (TCGA) database. The correlation between clinicopathological c…

lab-animal 2018
Materials (Basel, Switzerland) ·doi:10.3390/ma11030338

To improve the release profile of peptide drugs, thermos-responsive triblock copolymer poly (ε-caprolactone-co-p-dioxanone)-b-poly (ethylene glycol)-b-poly (ε-caprolactone-co-p-dioxanone) (PECP) was prepared and end capped by succinic anhyd…

rct 2016
·doi:10.3760/cma.j.issn.1674-4756.2016.21.034

Objective To observe the clinical effect of letrozole combined with metformin on endometriosis. Methods One hundred and twelve cases of endometriosis from October 2013 to November 2014 were randomly divided into control group and tre…

lab-animal 2015
Molecular Endocrinology ·doi:10.1210/me.2014-1292

The forkhead box O1A (FOXO1) is an early-induced target of the protein kinase A pathway during the decidualization of human endometrial stromal cells (HESCs). In this study we identified the cistrome and transcriptome of FOXO1 and its role …