Tiantian Wu

No ORCID on file · 3 papers in corpus · active 2025

Study types

  • other 2
  • article 1

Condition tags

  • endometriosis 3
other 2025
MEGF8-driven metabolic reprogramming and immune evasion define a high-risk subtype of endometriosis-associated ovarian cancer
American journal of translational research ·doi:10.62347/AOPY5249

OBJECTIVE: Endometriosis increases ovarian cancer (OC) risk through genetic mutations, chronic inflammation, and hormonal dysregulation, yet the underlying molecular pathways remain underexplored. This study aims to identify endometriosis-a…

other 2025
Single-cell and spatially resolved omics reveal transcriptional and metabolic signatures of ovarian endometriomas
Nature communications ·doi:10.1038/s41467-025-66706-8

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of…

article 2025
Single-cell transcriptome unveils mesenchymal cell diversity in endometriosis
Human molecular genetics ·doi:10.1093/hmg/ddaf065

Mesenchymal cells constitute the primary structural support elements within endometriotic lesions, yet their pivotal roles in endometriotic pathogenesis remain largely uncharted. This study aimed to construct a single-cell atlas of endometr…