Shuji Hirata

Objectives: The objective of this study was to observe the influence of laparoscopic adenomyomectomy on perinatal outcomes. Materials and Methods: The retrospective cohort study included 43 pregnant cases with adenomyosis who did not underg…

INTRODUCTION: Uterine adenomyosis is a benign disorder in which endometrial glands and stroma are present within the myometrium. There have been several case reports of cerebral infarction associated with adenomyosis, but their clinical cha…

Abstract Purpose It is unknown whether surgery for endometriosis or recurrence of endometriosis affects obstetric outcomes. Methods A total of 208 pregnant women with a history of endometriosis were analyzed. Patients who had endometriomas …

Sphingosine 1-phosphate (S1P), an inflammatory mediator, is abundantly contained in red blood cells and platelets. We hypothesized that the S1P concentration in the peritoneal cavity would increase especially during the menstrual phase due …

子宮内膜症患者では、腹腔内の免疫環境の異常が指摘されている。Macrophage(MΦ)は、腹腔内の主な免疫細胞で、炎症性疾患である子宮内膜症患者の腹腔内においては、抗炎症・免疫抑制性のM2 MΦが優位と報告されているが、なぜM2 MΦ優位なのか、M2 MΦが子宮内膜症の増悪あるいは抑制因子であるのか、その意義は明らかにされていない。我々は逆流月経血中のalarmin IL-33に着目し、IL-33が腹腔内免疫環境をM2 MΦ優位に誘導する因子の1つであることをin vitr…

As the number of women who postpone their first pregnancy until their late 30s or early 40s is increasing, adenomyosis is more frequently encountered by obstetricians. Some studies have reported on the relationship between adenomyosis and p…

•We present an unusual case of umbilical endometriosis and huge uterine leiomyomas with marked hydropic and cystic degeneration.•Although umbilical tumors are uncommon, the differential diagnosis should include umbilical endometriosis, part…