Mosconi L

No ORCID on file · 3 papers in corpus · active 2022-2026
2026
Premenopausal bilateral oophorectomy leads to steeper declines in gray matter volume and alterations in perfusion and brain bioenergetics.
Scientific reports ·doi:10.1038/s41598-026-47740-y

Hysterectomy is the second most common surgery among women in the United States, often performed alongside elective oophorectomy. Premenopausal bilateral oophorectomy (PO) causes abrupt endocrine disruption and has been linked to increased …

2026
Women's midlife: the front line of Alzheimer prevention.
The Journal of clinical investigation ·doi:10.1172/jci199832

Nearly two-thirds of patients with Alzheimer disease (AD) are women, most of them postmenopausal. While sex differences in AD have historically been attributed to women's relative longevity, accumulating evidence challenges that view, point…

2022
Endogenous and Exogenous Estrogen Exposures: How Women's Reproductive Health Can Drive Brain Aging and Inform Alzheimer's Prevention.
Frontiers in aging neuroscience ·doi:10.3389/fnagi.2022.831807

After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease (AD), the most common cause of dementia affecting over 24 million people worldwide. The prevalence of AD is higher in women than in men, with postmen…