Kun Qian

ORCID: 0000-0001-8063-457X · 14 papers in corpus
observational 2026
BMC pregnancy and childbirth ·doi:10.1186/s12884-026-09669-y

BackgroundThis study aimed to explore whether an endometrial thickness (EMT) cutoff of 7 mm or 8 mm was more appropriate to define thin endometrium (TE) from the perspective of miscarriage and obstetric-neonatal complications.MethodsWe cond…

nonrandomized-trial 2026
Molecular therapy : the journal of the American Society of Gene Therapy ·doi:10.1016/j.ymthe.2025.09.035

Clinical application of mesenchymal stem cells for endometrial repair has been hampered by variability in cell quality, large-scale production, and uncertainty regarding the optimal delivery route. In this study, we investigated the therape…

review 2026
Current issues in molecular biology ·doi:10.3390/cimb48080832

Background: This review aims to systematically summarize the lineage origins, subtype classification, and functional dynamics of endometrial macrophages, clarify their mechanisms of action in normal reproductive physiology (menstrual cycle,…

other 2025
Journal of ovarian research ·doi:10.1186/s13048-025-01619-0

Polycystic ovary syndrome (PCOS) is a common reproductive disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. The quality of oocytes in PCOS patients remains poor, leading to poor pregnancy outcomes. T…

observational 2025
Human reproduction open ·doi:10.1093/hropen/hoaf073

STUDY QUESTION: What are the impacts of different male infertility factors on embryological, cumulative pregnancy and neonatal outcomes of IVF/ICSI cycles? SUMMARY ANSWER: Some severe male infertility factors, i.e. severe oligoasthenozoosp…

other 2025
Journal of assisted reproduction and genetics ·doi:10.1007/s10815-025-03490-w

PURPOSE: To screen drug targets of ovarian aging from a genetic perspective. METHODS: Systematic analyses were conducted with cis-expression quantitative trait loci data of druggable genes extracted as instrument variables. Summary statist…

observational 2025
Reproductive health ·doi:10.1186/s12978-025-02166-z

BACKGROUND: Endometrial thickness independently predicts pregnancy outcomes in frozen embryo transfer (FET) cycles. Thin endometrium always results in implantation failure and worse obstetric-neonatal outcomes. However, it has not been repo…

observational 2024
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.14771

IntroductionPrevious studies have demonstrated that abnormal body mass index (BMI) is associated with adverse pregnancy outcomes in frozen-thawed embryo transfer cycles. However, the relationship between BMI and pregnancy and perinatal outc…

observational 2023
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1065291

BACKGROUND: There is a higher risk of preterm delivery (PTD) in singleton live births conceived after in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) compared with spontaneously conceived pregnancies. The objective of o…

observational 2023
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1238887

BACKGROUND: The utilization of frozen-thawed embryo transfer (FET) cycles has been linked to heightened risks of adverse perinatal outcomes. However, the potential association between adverse perinatal outcomes and distinct endometrial prep…

meta-analysis 2021
Frontiers in endocrinology ·doi:10.3389/fendo.2021.814648

BACKGROUND: Thin endometrium on ovulation triggering day is associated with impaired pregnancy outcomes in women after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), but the role of thick endometrium on pregnancy outcom…

2018
·doi:10.1016/j.fertnstert.2018.07.729
lab-animal 2014
Fertility and sterility ·doi:10.1016/j.fertnstert.2014.05.036

OBJECTIVE: To identify the expression profile and sex steroid regulation pattern of myeloid ecotropic viral integration site 1 (MEIS1) in endometrium. DESIGN: Molecular studies in human and animal tissue. SETTING: Reproductive medicine ce…

lab-animal 2008
Human reproduction (Oxford, England) ·doi:10.1093/humrep/den082

BACKGROUND: The HOXA10 homeobox gene controls embryonic uterine development and adult endometrial receptivity. The three-amino-acid loop extension (TALE) family homeobox genes like myeloid ecotropic viral integration site 1 (MEIS) provide e…