Debashis Ghosh

No ORCID on file · 4 papers in corpus · active 2021-2023

Study types

  • review 2
  • other 1

Condition tags

  • endometriosis 1
review 2023
Aromatase and steroid sulfatase from human placenta
Methods in enzymology ·doi:10.1016/bs.mie.2023.04.025

Cytochrome P450 aromatase (AROM) and steroid (estrone (E1)/dehydroepiandrosterone (DHEA)) sulfatase (STS) are the two key enzymes responsible for the biosynthesis of estrogens in human, and maintenance of the critical balance between androg…

other 2023
Structure of human placental steroid sulfatase at 2.0 angstrom resolution: Catalysis, quaternary association, and a secondary ligand site
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2022.106228

Human placental estrone (E1)/dehydroepiandrosterone (DHEA) sulfatase (human placental steroid sulfatase; hSTS) is an integral membrane protein of the endoplasmic reticulum. This Ca2+-dependent enzyme catalyzes the hydrolysis of sulfate este…

review 2023
Structures and functions of human placental aromatase and steroid sulfatase, two key enzymes in estrogen biosynthesis
Steroids ·doi:10.1016/j.steroids.2023.109249

Cytochrome P450 aromatase (AROM) and steroid sulfatase (STS) are the two key enzymes for the biosynthesis of estrogens in human, and maintenance of the critical balance between androgens and estrogens. Human AROM, an integral membrane prote…

2021
Host methylation predicts SARS-CoV-2 infection and clinical outcome
·doi:10.21203/rs.3.rs-334297/v1