I. Ryan

No ORCID on file · 6 papers in corpus · active 1994-2000

Study types

  • article 6

Condition tags

  • endometriosis 5
  • mesh:D004715 3
article 2000
Ovarian steroid and cytokine modulation of human endometrial angiogenesis
·doi:10.1093/humrep/15.suppl_3.67

A key mechanism underlying the cyclical growth of the endometrium is its ability to regenerate a vascular capillary network. In normal cycling human endometrium, angiogenesis is influenced by both endocrine and paracrine factors. Hormonal m…

article 1997
O-030 Induction of vascular endothelial growth factor and interleukin-6 expression in human endometriosis stromal cell cultures by interleukin-1 beta
·doi:10.1016/s0015-0282(97)90662-2
article 1996
Interleukin-6 secretion in vitro is up-regulated in ectopic and eutopic endometrial stromal cells from women with endometriosis.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.81.3.8772585

An in vitro model developed to compare human endometrial and endometriosis stromal cells was used to examine basal and stimulated expression of interleukin (IL-6). Stromal cells isolated from normal endometrium (NE) exhibited the lowest lev…

article 1996
Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.81.8.8768883

The human endometrium undergoes a complex process of vascular and glandular proliferation, differentiation, and regeneration with each menstrual cycle in preparation for implantation. Vascular endothelial growth factor (VEGF) is an endothel…

article 1996
Rantes chemokine expression is up-regulated in stromal cells cultured from human endometriosis tissues.
·doi:10.1016/1071-5576(96)82479-8
article 1994
Isolation, characterization, and comparison of human endometrial and endometriosis cells in vitro.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.78.3.8126136

Endometriosis is a common gynecological disorder of unclear pathogenesis. We have established an in vitro model to investigate phenotypic similarities and differences between normal endometrial and endometriosis cells. Highly purified cultu…