Xiaocan Lei

No ORCID on file · 3 papers in corpus
lab-animal 2024
Follicular fluid-derived extracellular vesicles miR-34a-5p regulates granulosa cell glycolysis in polycystic ovary syndrome by targeting LDHA
Journal of ovarian research ·doi:10.1186/s13048-024-01542-w

BACKGROUND: Polycystic ovary syndrome (PCOS) is highly prevalent in women of reproductive age worldwide, exhibits highly heterogeneous clinical presentation and biochemical parameters, and has no cure. This study aimed to investigate the ro…

meta-analysis 2024
MMP-9 as a clinical marker for endometriosis: a meta-analysis and bioinformatics analysis
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1475531

AIM: This study systematically evaluated the potential efficacy of serum matrix metalloproteinase-9 (MMP-9) concentration as a diagnostic marker for endometriosis through meta-analysis. Early and accurate diagnosis of endometriosis, a commo…

lab-animal 2022
Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome
Cell communication and signaling : CCS ·doi:10.1186/s12964-022-00876-6

OBJECTIVE: Polycystic ovary syndrome (PCOS) is characterized by follicular dysplasia. An insufficient glycolysis-derived energy supply of granulosa cells (GCs) is an important cause of follicular dysplasia in PCOS. Follicular fluid (FF) exo…