Li TT

No ORCID on file · 7 papers in corpus
lab-animal 2025
Nature communications ·doi:10.1038/s41467-025-65847-0

Despite intensive development, P2X7 modulators have struggled in translation due to human genetic variability and species-dependent drug responses. Here, we identify PSFL1191, a portal-of-central-pocket (PCP)-site inhibitor selective for hu…

meta-analysis 2022
Medicine ·doi:10.1097/md.0000000000029146

BACKGROUND: Antiphospholipid syndrome (APS) is an autoimmune disease that is associated with recurrent pregnancy loss. It is still controversial whether the presence of antiphospholipid antibodies (aPL) in the serum of patients with in vitr…

lab-animal 2019

Tian-Hong Zhu,1 Gen Zou,1 Shao-Jie Ding,1 Tian-Tian Li,1 Li-Bo Zhu,1 Jian-Zhang Wang,1 Yong-Xing Yao,2 Xin-Mei Zhang11Department of Obstetrics and Gynecology, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Repu…

lab-animal 2019
Journal of pain research ·doi:10.2147/jpr.s195909

Purpose: This study aimed to investigate the effect of oral treatment with ketotifen, a mast cell (MC) stabilizer, in a rat model of surgically induced endometriosis. Methods: At 14 days after Sprague-Dawley rats had surgery, they were trea…

other 2018
Zhonghua fu chan ke za zhi ·doi:10.3760/cma.j.issn.0529-567x.2018.03.005

Objective: To determine the levels of coagulation and inflammatory factors in women with moderate and severe ovarian endometriosis so as to investigate the possible role of coagulation and inflammatory factors in the pathogenesis, diagnosis…

other 2017
Reproduction (Cambridge, England) ·doi:10.1530/rep-17-0457

Endometriosis is an estrogen-dependent disease. Previous research has shown that abnormal enzymes associated with estrogen (E2) metabolism and an increased number of mast cells (MCs) in endometriomas are implicated in the pathogenesis of en…

observational 2017
Medicine ·doi:10.1097/md.0000000000006540

The effectiveness of thalidomide in treating inflammatory bowel disease (IBD) has been widely recognized. Meanwhile, many serious adverse drug reactions have been observed, but no know reports on ovarian reserve function.Female patients, ra…