Gonçalves GA

No ORCID on file · 5 papers in corpus
lab-animal 2018
Molecular medicine reports ·doi:10.3892/mmr.2018.9137

Endometriosis is a chronic gynecological disorder defined as the presence of endometrial tissue within extra-uterine sites. The primary symptoms are infertility and chronic pain. The inflammatory environment and aberrant immune responses in…

review 2017
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2017.11.026

p27kip1 as a key regulator of endometriosis Gonçalves GA p27kip1 is a cyclin-dependent kinase (CDK) inhibitor whose specific late G1 destruction allows progression of the cell across the G1/S boundary. There is a direct relationship between…

lab-animal 2017
Cytokine ·doi:10.1016/j.cyto.2015.12.015

Endometriosis is a gynecological benign chronic disease defined as the growth of endometrial glands and stroma in extra-uterine sites, most commonly implanted over visceral and peritoneal surfaces within the female pelvis causing inflammato…

lab-animal 2014
Apoptosis : an international journal on programmed cell death ·doi:10.1007/s10495-014-1079-8

We hypothesized that p27(kip1) overexpression can regulate endometriosis cell proliferation, apoptosis and vascular endothelial growth factor (VEGF) expression in the endometrium. The overexpression of p27(kip1) was obtained by transduction…

lab-animal 2013
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2013.01.034

Increased levels of hydrogen peroxide (H2O2) can initiate protective responses to limit or repair oxidative damage. However, H2O2 signals also fine-tune responses to growth factors and cytokines controlling cell division, differentiation, a…