Study types
- dataset 6
- article 5
- review 2
- other 1
- preprint 1
Condition tags
- adenomyosis 14
- mesh:D004715 1
- endometriosis 1
- infertility 1
Top journals
Frequent coauthors
- Wei Shi 15
- Zhi-yong Liu 14
- Xin Wang 12
- Li Xu 12
- Hong-Yun Liu 10
- Yanfei Wang 10
- Na Liang 9
- Weipin Niu 8
- Wang, Xin 8
- Zhonghua Sun 8
Adenomyosis (AM), an estrogen‑dependent chronic inflammatory disease with a rising incidence, has emerged as a major cause of infertility and reduced clinical pregnancy rates in reproductive‑aged women, severely impairing reproductive healt…
BACKGROUND: The active ingredients of the Chinese medical herb Paris polyphylla, P. polyphylla ethanol extract (PPE) and polyphyllin I (PPI), potentially inhibit epithelial-mesenchymal transition (EMT) in tumors. However, the roles of these…
Because adenomyosis (AM) ectopic primary cells are hard to come by, have a short lifespan, and the characteristics that alter over time, their utility in AM research is constrained. This study aimed to establish a line of immortalized human…
BACKGROUND: The effect of GuizhiFuling Wan (GFW) on adenomyosis (AM) is definite. This study aimed to explore the mechanism and key therapeutic targets of GFW in treating AM through network pharmacology combined with molecular docking and e…
Objective: Sm. (C-P) drug pair in the treatment of adenomyosis (AM) based on network pharmacology and animal experiments. Methods: Via a network pharmacology strategy, a drug-component-target-disease network (D-C-T-D) and protein-protein in…
Additional file 1: Figure S1. HE staining and QC. (A) Samples from the AM_CTRL, AM_EM and AM_EC groups were HE stained, and the black arrow shows the gland invading the muscular layer. (B) X axis represents the number of UMI in each cell, a…
Additional file 2: Table S1. Doublet score and predicted doublets.
Additional file 3: Table S2. DEGs of AM_EC vs. AM_EM (all cell types).
Additional file 4: Table S3. Coexisting genes in Venn.
Additional file 5: Table S4. DEGs of AM_EC vs. AM_EM (epithelial cells).
Additional file 6: Table S5. Clinical characteristics of AM patients and hysteromyoma samples used in this study.
BACKGROUND: Adenomyosis (AM) is a common benign chronic gynaecological disorder; however, the precise pathogenesis of adenomyosis is still poorly understood. Single-cell RNA sequencing (scRNA-seq) can uncover rare subpopulations, explore ge…
Endometriosis (EMs) is recorded as Zheng Jia in traditional Chinese medicine (TCM) books. Guizhi Fuling Pills (GFPs), a classic prescription for promoting blood circulation and removing blood stasis, is widely used for women's blood stasis …