Reddy DN

No ORCID on file · 3 papers in corpus
2022
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach.
Clinical proteomics ·doi:10.1186/s12014-022-09384-8

BackgroundThe progression of chronic pancreatitis (CP), an inflammatory disease of the pancreas, causes pancreatic stones to form within the pancreatic ductal lumen/parenchyma, which occurs via protein plug formation. Pain is the most commo…

2011
Assessing the pathological relevance of SPINK1 promoter variants.
European journal of human genetics : EJHG ·doi:10.1038/ejhg.2011.79

The SPINK1 gene, encoding the human pancreatic secretory trypsin inhibitor, is one of the major genes involved in predisposition to chronic pancreatitis (CP). In this study we have assessed the potential functional impact of 11 SPINK1 promo…

2009
Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis.
World journal of gastroenterology ·doi:10.3748/wjg.15.264

Chronic pancreatitis is known to be a heterogeneous disease with varied etiologies. Tropical calcific pancreatitis (TCP) is a severe form of chronic pancreatitis unique to developing countries. With growing evidence of genetic factors contr…