Malpani SS

No ORCID on file · 3 papers in corpus
lab-animal 2016
Fenretinide: A Potential Treatment for Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116632920

OBJECTIVE: Fenretinide is a synthetic retinoid analogue that promotes apoptosis but has decreased toxicity when compared to other retinoids. We have previously shown that retinoic acid (RA) production in endometriotic tissue is decreased, r…

lab-animal 2015
Aberrant expression and localization of deoxyribonucleic acid methyltransferase 3B in endometriotic stromal cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.06.046

OBJECTIVE: To define the expression and function of DNA methyltransferases (DNMTs) in response to decidualizing stimuli in endometriotic cells compared with healthy endometrial stroma. DESIGN: Basic science. SETTING: University research c…

lab-animal 2014
ERβ- and prostaglandin E2-regulated pathways integrate cell proliferation via Ras-like and estrogen-regulated growth inhibitor in endometriosis
Molecular Endocrinology ·doi:10.1210/me.2013-1421

In endometriosis, stromal and epithelial cells from the endometrium form extrauterine lesions and persist in response to estrogen (E2) and prostaglandin E2 (PGE2). Stromal cells produce excessive quantities of estrogen and PGE2 in a feed-fo…