Allan GF

No ORCID on file · 2 papers in corpus
other 2006
Molecular properties and preclinical pharmacology of JNJ-1250132, a steroidal progesterone receptor modulator that inhibits binding of the receptor to DNA in vitro
Steroids ·doi:10.1016/j.steroids.2006.02.002

Progesterone receptor modulators have diverse potential therapeutic uses, including the treatment of endometriosis, uterine fibroids and breast cancer. Here we describe the molecular properties and preclinical pharmacology of a new steroida…

2005
Non-steroidal progesterone receptor specific ligands.
Mini reviews in medicinal chemistry ·doi:10.2174/1389557054553794

The nuclear receptor for progesterone is a target for contraception and for several therapeutic indications. Progestin agonists and antagonists in clinical use mimic the steroidal backbone of the cognate ligand, progesterone. Thus, they hav…