Özlem Bozoklu Akkar

No ORCID on file · 3 papers in corpus
article 2016
Elevated Serum CD95/FAS and HIF-1α Levels, but Not Tie-2 Levels, May Be Biomarkers in Patients With Severe Endometriosis: A Preliminary Report
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2016.01.025

Study objectiveTo evaluate serum values of cluster of differentiation 95 (CD95/FAS), hypoxia-inducible factor 1-alpha (HIF-1α), and tyrosine kinase receptor 2 (Tie-2) as possible biomarkers of disease presence and severity in women with end…

article 2015
Effects of Pazopanib, Sunitinib, and Sorafenib, Anti-VEGF Agents, on the Growth of Experimental Endometriosis in Rats
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115584448

We aimed to compare the effects of pazopanib, sunitinib, and sorafenib on endometriotic tissue morphology and histological characteristics as well as ovarian reserve in a rat model. Experimental endometriosis was established in 32 rats. The…

article 2012
The Efficacy of Bevacizumab, Sorafenib, and Retinoic Acid on Rat Endometriosis Model
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719112452941

Blood vessels are necessary for development and maintenance of the endometriosis and blood flow supplies oxygen and essential nutrient to the disease. Local angiogenesis is regulated by vascular endothelial growth factor (VEGF) and inhibito…