Sebastian D Schäfer

No ORCID on file · 9 papers in corpus · active 2016-2026

Study types

  • article 6
  • other 3

Condition tags

  • endometriosis 8
  • mesh:D004715 3
  • infertility 1
other 2026
Diagnosis and Therapy of Endometriosis. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/045, April 2025)
Geburtshilfe und Frauenheilkunde ·doi:10.1055/a-2760-4867

Objective The objective of this revised official guideline, published by the German Society for Gynecology and Obstetrics (DGGG) and coordinated in the joint guidelines program of the DGGG, the Austrian Society for Gynecology and Obstetrics…

article 2025
Combined targeting of TCF7L1 /2, PTEN , CDK6 , and BCCIP by microRNA miR ‐29c‐3p is associated with reduced invasion and proliferation of endometriotic cells
Reproductive medicine and biology ·doi:10.1002/rmb2.12645

Abstract Purpose Endometriosis is a chronic gynecological disorder associated with pain symptoms and infertility. The expression of microRNA miR‐29c‐3p is dysregulated in endometriosis. We aimed to identify novel molecular targets of miR‐29…

other 2024
Assessment of the Ferroptosis Regulators: Glutathione Peroxidase 4, Acyl-Coenzyme A Synthetase Long-Chain Family Member 4, and Transferrin Receptor 1 in Patient-Derived Endometriosis Tissue
Biomolecules ·doi:10.3390/biom14070876

Ferroptosis, an iron-dependent form of non-apoptotic cell death, plays a pivotal role in various diseases and is gaining considerable attention in the realm of endometriosis. Considering the classical pathomechanism theories, we hypothesize…

other 2024
Influence of App-Based Self-Management on the Quality of Life of Women With Endometriosis
Cureus ·doi:10.7759/cureus.67655

INTRODUCTION: Endometriosis can significantly impair the quality of life of those affected. Multimodal self-help measures are recommended but are often difficult to access. Smartphone apps have been shown to improve the quality of life for …

article 2021
Collagen I triggers directional migration, invasion and matrix remodeling of stroma cells in a 3D spheroid model of endometriosis
Scientific reports ·doi:10.1038/s41598-021-83645-8

Endometriosis is a painful gynecological condition characterized by ectopic growth of endometrial cells. Little is known about its pathogenesis, which is partially due to a lack of suitable experimental models. Here, we use endometrial stro…

article 2021
Diagnosis and Treatment of Endometriosis. Guideline of the DGGG, SGGG and OEGGG (S2k Level, AWMF Registry Number 015/045, August 2020)
Geburtshilfe und Frauenheilkunde ·doi:10.1055/a-1380-3693

Abstract Aims The aim of this official guideline published and coordinated by the German Society of Gynaecology and Obstetrics (DGGG) in cooperation with the Austrian Society for Gynaecology and Obstetrics (OEGGG) and the Swiss Society for …

article 2020
miR-142-3p Reduces the Size, Migration, and Contractility of Endometrial and Endometriotic Stromal Cells by Targeting Integrin- and Rho GTPase-Related Pathways That Regulate Cytoskeletal Function
Biomedicines ·doi:10.3390/biomedicines8080291

Downregulated microRNA-142-3p signaling contributes to the pathogenesis of endometriosis, an invasive disease where the lining of the uterus grows at ectopic locations, by yet incompletely understood mechanisms. Using bioinformatics and in …

article 2019
γ‐Secretase inhibition affects viability, apoptosis, and the stem cell phenotype of endometriotic cells
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.13707

INTRODUCTION: Stem cells mediate cyclic regeneration of the endometrium. The upregulated expression of receptors and modulators of the notch signaling pathway in endometriosis suggests an involvement in the pathogenetic process. Here, we in…

article 2016
microRNA miR-200b affects proliferation, invasiveness and stemness of endometriotic cells by targeting ZEB1, ZEB2 and KLF4
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2015.12.013