Michael W. Vernon

article 2017

Stress During Development of Experimental Endometriosis Influences Nerve Growth and Disease Progression

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719117737846

PurposeWe have previously shown that stress prior to induction worsens clinical presentation and inflammatory parameters in a rat model of endometriosis. This study was designed to examine whether stress during the development of endometrio…

article 2009

Klassifikation der Endometriose durch Morphologie und Prostaglandin-F-Synthesekapazität

·doi:10.1159/000270569

other 2007

Molecular profiling of experimental endometriosis identified gene expression patterns in common with human disease

Fertility and sterility ·doi:10.1016/j.fertnstert.2006.07.1550

OBJECTIVE: To validate a rat model of endometriosis using complimentary DNA (cDNA) microarrays by identifying common gene expression patterns between experimental and natural disease. DESIGN: Autotransplantation rat model. SETTING: Medica…

article 1993

The presence of luteinized unruptured follicle syndrome and altered folliculogenesis in rats with surgically induced endometriosis

American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(93)90642-v

ObjectiveOur purpose was to determine in the rat model whether endometriosis could influence ovarian function by altering oocyte release or folliculogenesis.Study designWe histologically examined the ovaries of reproductively cycling rats w…

article 1991

Spontaneous and steroid-induced recurrence of endometriosis after suppression by a gonadotropin-releasing hormone antagonist in the rat

American journal of obstetrics and gynecology ·doi:10.1016/0002-9378(91)90652-8

Recurrent endometriosis in women is difficult to study because of the ethical consideration of performing repeated surgeries. Previously in the rat model we described therapeutic regression of endometriosis with the gonadotropin-releasing h…

article 1990

Follicular Atresia and Infertility in Rats Treated with a Gonadotropin-Releasing Hormone Antagonist*

Endocrinology ·doi:10.1210/endo-127-1-25

Adverse effects of the GnRH antagonist Antide on folliculogenesis and fertility were noted when we were evaluating the therapeutic value of Antide on endometriosis in a rat model. Cyclic rats with (n = 56) and without (n = 18) surgically in…

article 1986

Classification of endometriotic implants by morphologic appearance and capacity to synthesize prostaglandin F

Fertility and sterility ·doi:10.1016/s0015-0282(16)49814-6

The severity of the symptoms of endometriosis has not always correlated well with the anatomic severity of the disease. This lack of correlation may be due to variations in the metabolic activity of the endometriotic implants present at dif…