Malcolm Whitehead

article 1997

Endometrial effects of three doses of trimegestone, a new orally active progestogen, on the postmenopausal endometrium

·doi:10.1016/s0378-5122(97)00058-3

ObjectiveTo study the effects of oral trimegestone on endometrial histology and vaginal bleeding when given in combination with oral 17-beta-oestradiol.MethodsThis was a prospective, randomised, double-blind, parallel groups, pilot comparat…

article 1992

Danazol induces resistance to both insulin and glucagon in young women

Clinical science (London, England : 1979) ·doi:10.1042/cs0820211

1. Danazol elevates plasma insulin, plasma glucagon and serum low-density lipoprotein concentrations and reduces the serum high-density lipoprotein concentration. 2. Associations between these disturbances were studied in 17 women receiving…

article 1989

Are fixed‐dose oestrogen/progestogen combinations ideal for all HRT users?

·doi:10.1111/j.1471-0528.1989.tb03315.x

Although progestogens protect the endometrium against excessive oestrogen-induced stimulation, they can cause adverse symptomatic and psychological effects and may have undesirable metabolic consequences. Thus, the minimum progestogen dose …

article 1986

Effects of dydrogesterone on the oestrogenized postmenopausal endometrium

·doi:10.1111/j.1471-0528.1986.tb07814.x

Postmenopausal women receiving conjugated oestrogens 1.25 mg daily continuously were also given dydrogesterone either 5, 10 or 20 mg daily for the first 12 days of each calendar month. Endometrial tissue obtained on the sixth day of combine…