Oskotsky B

No ORCID on file · 4 papers in corpus
2026
·doi:10.21203/rs.3.rs-10606217/v1

Abstract Background Transcriptome-based drug repurposing can accelerate therapeutic discovery, but is limited by fragmented resources, inconsistent quality control, and reliance on single perturbation databases. Methods We developed CD…

2026
bioRxiv : the preprint server for biology ·doi:10.64898/2026.07.17.739227

Transcriptome-based drug repurposing can accelerate therapeutic discovery, but is limited by fragmented resources, inconsistent quality control, and reliance on single perturbation databases. We developed CDRPipe (Computational Drug Repurpo…

other 2025
Cell reports methods ·doi:10.1016/j.crmeth.2025.101137

High-throughput sequencing enables efficient processing of DNA and RNA samples in batches, but batch effects can obscure true biological signal. We propose using anticlustering as an automated method to assign samples to balanced batches, m…

2025
·doi:10.1101/2025.03.03.641320

High throughput sequencing is a powerful tool for processing large amounts of DNA and RNA samples in batches. Proper experimental design and statistical methods are required to mitigate systematic technical factors due to differences in bat…