OBJECTIVE: To examine clinicopathologic characteristics and oncologic outcomes of patients diagnosed with Mullerian adenosarcoma and to evaluate ovarian preservation as a practical management option in early-stage disease. METHODS: A retro…
Purpose: Uterine serous carcinoma (USC) is a rare and aggressive variant of endometrial cancer. Whole-exome sequencing (WES) studies have recently reported c-Myc gene amplification in a large number of USCs, suggesting c-Myc as a potential …
Ovarian cancer (OC) is the single most deadly form of women's cancer, typically presenting as an advanced disease at diagnosis in part due to a lack of known risk factors or genetic markers of risk. The KRAS oncogene and altered levels of t…
Clear cell adenocarcinoma of the colon is rare, with only a handful of cases reported in the literature. Some of these cases are attributed to endometriotic involvement of the colonic wall; however, a presence of the clear cell adenocarcino…
OBJECTIVE: Endometrial cancer (EC) is the most common gynecologic malignancy. Type I EC has a favorable prognosis, while type II ECs account for half of all treatment failures. Little knowledge of the biological differences is available to …
Endometrial polyp is the most frequent tumor-like condition, involving usually the first segment of the fallopian tube and resulting in infertility and ectopic pregnancy. Salpingitis, either acute or chronic, can cause tubal enlargement and…
Primary peritoneal tumors and tumor-like conditions of secondary mullerian system include various endometrioid, serous, and mucinous lesions. Endometriosis is the most common tumor-like condition resulting in a significant morbidity in wome…
Ovarian primary carcinoid tumors of pure histological type can pose a significant diagnostic challenge in its separation from metastatic carcinoids from the gastrointestinal tract. Yet, their clinical management and prognosis are drasticall…