Ruoshui Chang

No ORCID on file · 4 papers in corpus
article 2026
TREM2 Deficiency Attenuates Endometriosis Progression by Inhibiting M2 Polarization of SpMs and Suppressing SIRPα to Enhance Phagocytosis
Biology of reproduction ·doi:10.1093/biolre/ioag159

Endometriosis (EMS) is characterised by a disrupted peritoneal immune microenvironment where M2 macrophage polarization and impaired phagocytosis promote lesion survival. Single-cell RNA-seq (ScRNAseq) of the peritoneal macrophages from EMS…

article 2025
Heme Inhibits the STING Pathway in Macrophages to Promote Endometriosis Development
·doi:10.1016/j.jri.2025.104695
preprint 2025
Hemin Inhibits the Activation of STING in Macrophages by Inducing HO-1, Promoting Endometriosis Development
·doi:10.1101/2025.10.25.683839

Abstract Introduction Endometriosis (EMS) is an estrogen-dependent inflammatory disorder characterized by immune dysregulation. This condition profoundly affects the quality of life and reproductive health of nearly 200 million women of rep…

review 2025
The role of macrophage in endometriosis and endometriosis-associated ovarian cancer
Expert reviews in molecular medicine ·doi:10.1017/erm.2025.10012