Niu Y

BACKGROUND: This retrospective study aimed to evaluate the association between endometrial thickness (EMT) on the day of human chorionic gonadotropin (hCG) trigger and the cumulative live birth rate (CLBR) across one oocyte-retrieval cycle.…

ObjectivesThis study aimed to examine the associations between shift work and menstrual disorders among female nurses and to explore the potential mediating role of sleep quality in these relationships.MethodsA cross-sectional study was con…

Bisphenol A (BPA), an endocrine-disrupting chemical frequently detected in follicular fluid (FF), has been implicated in ovarian reserve dysfunction. However, data on the presence of its structural analogues within ovarian follicles remain …

BACKGROUND: While chemotherapy is central to gestational trophoblastic disease (GTD) management, concerns over toxicity and resistance have renewed interest in hysterectomy. This study evaluated outcomes of patients treated with hysterectom…

OBJECTIVE: To investigate the impact of thyroid autoimmunity (TAI) on fertilization outcomes in euthyroid infertile women undergoing in vitro fertilization-embryo transfer (IVF-ET), and to identify key follicular fluid exosomal miRNAs assoc…

BACKGROUND: Although the cardiometabolic index (CMI) has gained recognition as a new tool for evaluating metabolic health, the relationship between CMI and cardiovascular disease (CVD) remains unclear. This research sought to explore the po…

PURPOSE: To explore the impact of seasonal variations on the risks of hypertensive disorders of pregnancy (HDP) and gestational diabetes mellitus (GDM) in women who undergo in vitro fertilization (IVF) treatment. METHODS: We retrospectivel…

BACKGROUND: Infertility in women of reproductive age is a major worldwide health problem. Oxidative stress, inflammatory responses, and dysregulation of lipid metabolism are among the factors that contribute to female infertility. The ratio…

BACKGROUND: Uterine fibroids and endometriosis are common benign gynecological diseases affecting the health of women of childbearing age, characterized by high incidence and recurrence rates. Despite the increasing global emphasis on women…

Alternative polyadenylation (APA) is a critical post-transcriptional regulatory mechanism, yet its role in follicular development and atresia in waterfowl remains poorly understood. To address this, we performed full-length transcriptome se…

BACKGROUND: Hypertensive disorders of pregnancy (HDP) and gestational diabetes mellitus (GDM) are common complications that adversely affect pregnancy outcomes. However, data on their independent and combined impacts on fetal growth and per…

BACKGROUND: Thin endometrium (TE) is associated with impaired endometrial receptivity and reduced rates of successful pregnancy. However, the immune-related transcriptomic alterations underlying TE remain poorly understood. This study aimed…

BACKGROUND: Endometriosis is an estrogen-dependent disorder with unclear molecular mechanisms. Ferroptosis, a regulated iron-dependent cell death, may play a key role, yet the specific genes involved remain underexplored. METHODS: Ferropto…

In the field of genetic breeding, primordial germ cells (PGCs) have become essential cells for gene editing and genetic improvement due to their unique developmental potential and genetic characteristics. However, the low proliferation effi…

OBJECTIVE: Advanced gastric cancer remains highly refractory to therapy, with limited immunotherapy efficacy due to tumor microenvironment heterogeneity. Primary cilia, microtubule-based organelles involved in tumor progression, remain insu…

PURPOSE: To investigate the effects of fresh embryo transfer and frozen-thawed embryo transfer on perinatal outcomes among patients with PCOS. METHOD: Patients who underwent in vitro fertilization and embryo transfer at the reproductive me…

PURPOSE: To explore whether the risks of early- or late-onset preeclampsia vary among frozen embryo transfer (FET) with different regimens for endometrial preparation and fresh embryo transfer (FreET). METHODS: We retrospectively included …

BACKGROUND: Hormone replacement therapy (HRT) regimen was suggested to be associated with a decreased rate of livebirth and a higher risk of hypertensive disorders of pregnancy (HDP) after frozen cleavage stage embryo transfer in women with…

BACKGROUND: Idiopathic hypogonadotropic hypogonadism (IHH) is a rare genetic disease attributed to the disorder of hypothalamic-pituitary-gonadal axis. Mutations in the GNRHR gene are one of the most common genetic causes of IHH. Herein, we…

Recurrent implantation failure (RIF) is an intrigue condition during in vitro fertilization (IVF) cycles or intracytoplasmic sperm injection (ICSI) treatments. The purpose of this retrospective study is to explore the value of next-generati…

Patrinia scabiosaefolia is a medical and edible Chinese herb with high nutritional and medicinal value. The continuing study of its chemical constituents led to the discovery of nine unique iridoids and iridoid glycosides, including three n…

OBJECTIVE: Concern regarding the adverse impact of pretreatment of oral contraceptives (OC) prior to ovarian stimulation for in vitro fertilization (IVF) on pregnancy outcome has been debated. We investigated factors that may be associated …

Caulis Sargentodoxae prescription has been confirmed by the gynecological clinical observation to be effective in the treatment of endometriosis (EMs), and inflammatory cytokines were involved in EMs. In this paper, animal experiments were …

OBJECTIVE: To use proteomic techniques, including two-dimensional electrophoresis (2-DE), Western blot, and mass spectrometry, to screen and identify proteins that were expressed differently in patients with endometriosis versus normal cont…