Scott D. Mendelson

No ORCID on file · 6 papers in corpus
lab-animal 2010
·doi:10.14288/1.0098144

In 1985, Mendelson and Gorzalka proposed the dual role hypothesis of serotonergic modulation of lordosis behaviour. In this hypothesis it was proposed that serotonergic activity can either inhibit or facilitate lordosis behaviour. Specifica…

lab-animal 1990
Neuropharmacology ·doi:10.1016/0028-3908(90)90133-c

Peripheral administrations of TFMPP (0.2- 1 mg/kg) or MCPP (1 mg/kg) facilitated lordosis behavior in female rats treated with estradiol benzoate, and had no effects in females primed with estradiol benzoate and progesterone. In contrast, T…

lab-animal 1988
Pharmacology, biochemistry, and behavior ·doi:10.1016/0091-3057(88)90193-1

Existing reports on the effects of beta-adrenergic antagonists on lordosis behavior appear contradictory, with (+/-) propranolol being reported to inhibit, and (+/-) pindolol to facilitate this behavior. In the present study, both the (-) a…

lab-animal 1987
European journal of pharmacology ·doi:10.1016/0014-2999(87)90086-0

Intraventricular administration of the tryptophan metabolites l-kynurenine (2-32 micrograms) and kynuramine (0.064-8 micrograms) facilitated lordosis behavior in estrogen-primed ovariectomized rats. The facilitatory effects of these drugs w…

lab-animal 1986
European journal of pharmacology ·doi:10.1016/0014-2999(86)90625-4

Ipsapirone and gepirone, but not buspirone, facilitated lordosis in estrogen-treated rats, whereas all three drugs inhibited this behavior in rats treated with estrogen and progesterone. When administered at higher doses, ipsapirone, gepiro…

lab-animal 1986
Life sciences ·doi:10.1016/0024-3205(86)90272-9

The theory that activation of serotonin type 2 (5-HT2) receptors facilitates lordosis behavior in the female rat was tested. The 5-HT2 antagonists pizotefin, cyproheptadine, metitepine, and ketanserin were found to inhibit lordosis behavior…