Mana Hirano

No ORCID on file · 12 papers in corpus
case-report 2025
BMC women's health ·doi:10.1186/s12905-025-03681-8

BACKGROUND: Adenomyosis, characterized by endometrial tissue within the uterine muscle, often presents with severe pelvic pain and menorrhagia. This case series demonstrates the efficacy of sequential therapy involving relugolix followed by…

observational 2024
Journal of ovarian research ·doi:10.1186/s13048-024-01494-1

BACKGROUND: Interval debulking surgery (IDS) following neoadjuvant chemotherapy is a treatment option for advanced ovarian cancer. Optimal surgery is required for better survival; however, while peritoneal washing cytology (PWC) has been id…

other 2024
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15993

AIM: As a treatment for tubal infertility, falloposcopic tuboplasty (FT) is one of the options for patients who wish to conceive naturally. Based on the results of FT, we propose an appropriate time of transitioning to assisted reproductive…

lab-animal 2024
Reproductive toxicology (Elmsford, N.Y.) ·doi:10.1016/j.reprotox.2024.108571

Ulipristal (UPA), a selective progesterone receptor modulator, has both agonistic and antagonistic effects on progesterone receptors. UPA suppresses ovulation by inhibiting the luteinizing hormone (LH) surge from the pituitary gland; howeve…

lab-animal 2023
·doi:10.21203/rs.3.rs-2847062/v1

Abstract Ulipristal (UPA), a selective progesterone receptor modulator, has both agonistic and antagonistic effects on progesterone receptors. UPA suppresses ovulation by inhibiting the luteinizing hormone (LH) surge from the pituitary glan…

case-report 2022
Frontiers in oncology ·doi:10.3389/fonc.2022.1079716

BACKGROUND: Lenvatinib-pembrolizumab combination (LEAP) is an approved therapy in Japan for advanced endometrial cancer, based on the data from the KEYNOTE-775 clinical trial. We report a case of posterior reversible encephalopathy syndrome…

observational 2022

Aim: Endometriosis is linked to asymptomatic atherosclerosis and increases the risk of cardiovascular disease (CVD). Vascular function tests are used to assess atherosclerosis, an important indicator of CVD development. In this study, we ai…

observational 2022
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.15447

AIM: Endometriosis is linked to asymptomatic atherosclerosis and increases the risk of cardiovascular disease (CVD). Vascular function tests are used to assess atherosclerosis, an important indicator of CVD development. In this study, we ai…

observational 2022
Endocrine journal ·doi:10.1507/endocrj.ej22-0158

Dienogest (DNG) is widely used to treat dysmenorrhea associated with estrogen-dependent diseases such as endometriosis and adenomyosis. DNG becomes unnecessary after menopause when estrogen secretion declines drastically. However, there are…

observational 2022
BMC women's health ·doi:10.1186/s12905-022-01711-3

BACKGROUND: In women with endometriosis, the association between ovarian function, hormones, and bone mineral density (BMD) is unclear. Therefore, this study aimed to elucidate the association between changes in bone mineral density (BMD) a…

observational 2021
·doi:10.21203/rs.3.rs-778798/v1

Abstract Background In women with endometriosis, the association between ovarian function, hormones, and bone mineral density (BMD) is unclear. Therefore, this study aimed to elucidate the correlation between changes in bone mineral density…

2018