Dagdas G

No ORCID on file · 3 papers in corpus
lab-animal 2024
A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis
Nature communications ·doi:10.1038/s41467-024-45338-4

The common human SNP rs3820282 is associated with multiple phenotypes including gestational length and likelihood of endometriosis and cancer, presenting a paradigmatic pleiotropic variant. Deleterious pleiotropic mutations cause the co-occ…

lab-animal 2024
Hallmarks of uterine receptivity predate placental mammals
·doi:10.1101/2024.11.04.621939

Embryo implantation is essential to pregnancy in eutherian (placental) mammals. The cellular changes that enabled invasive implantation to evolve from superficial embryo apposition, the ancestral condition still retained in marsupials, have…

lab-animal 2022
A SNP affects Wnt4 expression in endometrial stroma, with antagonistic implications for pregnancy, endometriosis and reproductive cancers
·doi:10.1101/2022.10.25.513653

Abstract The common human single nucleotide polymorphism rs3820282 is associated with multiple phenotypes ranging from gestational length to likelihood of endometriosis and ovarian cancer and can thus serve as a paradigm for a highly pleiot…