Othman ER

Current medical treatment options for endometriosis associated pains are inadequate. Evidence on effects of nonsteroidal anti-inflammatory drugs is scarce. Around one third of patients are not responsive to oral contraceptives or progestins…

Essam R Othman,1,2 Ayman Al-Hendy,3 Radwa Mostafa,1 Cornelis B Lambalk,2 Velja Mijatovic2 1OB-GYN Department, Assiut University, Assiut, 71515, Egypt; 2Academic Endometriosis Center, Amsterdam University Medical Center, Vrije Universiteit A…

OBJECTIVE: Endometriosis is a chronic debilitating inflammatory condition characterized by the presence of endometrial tissues outside the uterine cavity. Pelvic soreness and infertility are the usual association. Due to the poor effectiven…

Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide. The tropism of HEV is not restricted to the liver, and the virus replicates in other organs. Not all the extrahepatic targets for HEV are identified. Herei…

We aimed to investigate the effect of adding sildenafil vaginal gel to clomiphene citrate (CC) in infertile women with prior CC failure.MethodsThis is a self- controlled clinical trial. Women with CC failure (in prior 5 cycles) and thin end…

ObjectiveTo study Thy1 as a fibroblast marker, SSEA1 as a marker of intermediate pluripotency, and Oct4 as a marker of established pluripotency in rat model of endometriosis.DesignIn vivo animal study.Materials and methodsEndometriosis was …

IntroductionWe examine serum levels sTNFR-I and sTNFR-II in endometriosis patients, and their role as biomarkers of endometriosis.Material and methodsWomen were diagnosed with endometriosis during laparoscopy to investigate pelvic pain and/…

Endometriosis is a chronic recurrent disease that is relatively common. Diagnosis is difficult and often delayed. Current treatments are inadequate with unacceptable side effects and multiple surgeries may be needed. Abnormal eutopic endome…