Dong-Kee Lee

No ORCID on file · 4 papers in corpus · active 2007-2014

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 3
  • infertility 1
article 2014
Suppression of COUP-TFII by Proinflammatory Cytokines Contributes to the Pathogenesis of Endometriosis
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2013-3717

CONTEXT: Endometriosis is one of the most common gynecological diseases in women with a prevalence rate of approximately 10%. Chronic pelvic inflammation has been observed in patients with endometriosis and is associated with disease severi…

article 2011
Nuclear Orphan Receptor, COUP-TFII, in Reproduction.
·doi:10.1093/biolreprod/85.s1.162

COUP-TFII is an orphan nuclear receptor of the nuclear receptor superfamily. COUP-TFII is highly expressed in the uterine stroma and its expression is controlled by progesterone-Ihh-Ptch signaling from the epithelium to the stroma. Mutants …

article 2009
ERBB Receptor Feedback Inhibitor 1 Regulation of Estrogen Receptor Activity Is Critical for Uterine Implantation in Mice1
Biology of reproduction ·doi:10.1095/biolreprod.109.081307

Normal endometrial function requires a balance of progesterone (P4) and estrogen (E2) effects. E2 acts to stimulate the proliferation of uterine epithelial cells, while P4 action inhibits E2-mediated proliferation of the epithelium. P4 thro…

other 2007
COUP-TFII mediates progesterone regulation of uterine implantation by controlling ER activity
PLoS genetics ·doi:10.1371/journal.pgen.0030102

Progesterone and estrogen are critical regulators of uterine receptivity. To facilitate uterine remodeling for embryo attachment, estrogen activity in the uterine epithelia is attenuated by progesterone; however, the molecular mechanism by …