Isao Kurihara

COUP-TFII is an orphan nuclear receptor of the nuclear receptor superfamily. COUP-TFII is highly expressed in the uterine stroma and its expression is controlled by progesterone-Ihh-Ptch signaling from the epithelium to the stroma. Mutants …

Progesterone and estrogen are critical regulators of uterine receptivity. To facilitate uterine remodeling for embryo attachment, estrogen activity in the uterine epithelia is attenuated by progesterone; however, the molecular mechanism by …