E Simpson

No ORCID on file · 3 papers in corpus
article 2018
·doi:10.31032/ijbpas/2018/7.9.4548

Endometriosis is the primary cause of female infertility during reproductive age. It is due to the existence of endometrial glands and stromal tissues outside the wall of uterus. The particular prevalence of the disease is still unclear but…

review 2000
Trends in endocrinology and metabolism: TEM ·doi:10.1016/s1043-2760(99)00216-7

In contrast to normal endometrium, the expression of aromatase is aberrant in endometriosis and is stimulated by prostaglandin E2 (PGE2). This results in local production of estrogen, which induces PGE2 formation and establishes a positive …

review 1999
Endocrine-related cancer ·doi:10.1677/erc.0.0060293

Estrogen is the most important known factor that stimulates the growth of endometriosis. Estrogen delivery to endometriotic implants was classically viewed to be only via the circulating blood in an endocrine fashion. We recently uncovered …