Diane S. Nakamura

BACKGROUND: Angiogenesis is an essential process in endometriosis disease progression. Earlier, we demonstrated that anti-angiogenic peptide, ABT-898 prevents neoangiogenesis of human endometriotic lesions in a xenograft mouse model. Since …

Endometriosis is a gynecological disease defined by the growth of endometrium outside of the uterus. Although endometriosis contributes to 50 % of female infertility cases, medical treatments are incompatible with pregnancy. Angiogenesis, t…

Endometriosis is a gynecological disease defined by the growth of endometrium outside of the uterus. Although endometriosis contributes to 50% of female infertility cases, medical treatments are incompatible with pregnancy. Angiogenesis, th…

Cytokines present within the environment of endometriosis are believed to contribute to the pathogenesis of the disease by promoting inflammatory conditions surrounding the implantation of endometriotic lesions. Interleukin‐17A is a member …

Endometriosis is a gynecological disease characterized by the growth of endometrium outside of the uterine cavity. It is often associated with dysmenorrhea, dyspareunia, pelvic pain and infertility. One of the key requirements for endometri…

Endometriosis is a gynecological disease defined as the growth of endometrium outside of the uterus.Although linked to 50% of female infertility cases, current medical treatments fail to maintain fecundity.Since the survival of endometrioti…

Endometriosis is a common cause of pelvic pain and infertility in women, and a common indication for hysterectomy, yet the disease remains poorly diagnosed and ineffectively treated. Because endometriotic lesions require new blood supply fo…