M Canis

5To whom correspondence should be addressed Endometriosis is a multifactorial disease with possible genetic predisposition and involvement of environ-mental factors in its pathogenesis. The genetic polymorphism of glutathione S-transferase …

OBJECTIVE: While association between endometriosis and infertility is well established, there are few studies about the impact of endometriosis on adverse pregnancy outcomes. The aim of this study was to determine the effect of endometriosi…

Benign ovarian tumors can be separated in three groups: teratoma, unilocular cyst and endometrioma. Laparoscopy should always be preferred for the surgical approach. Before menopause, conservative treatment should be preferred apart from pr…

OBJECTIVE: To evaluate in infertile women the benefit of laparoscopic surgical treatment of endometriosis. PATIENTS AND METHODS: All infertile patients aged 18 to 43 years old, operated between February 2004 and March 2008, with a minimal …

Good knowledge of physiopathology, surgical techniques and of the literature allows for an adequate treatment of ovarian endometrioma. Preoperative medical treatment has not shown to be efficient and might be adapted to each patient (contin…

OBJECTIVE: to evaluate the complications after surgery for deep endometriosis. DESIGN: retrospective study. SETTING: data from the CHU Estaing database and patients' charts between January 1987 and December 2007. SAMPLE: all women given …

Thirty-one patients complaining of unexplained infertility for at least 36 months and diagnosed elsewhere were reassessed laparoscopically. After staining their pelvic peritoneum with concentrated methylene blue, they presented with extensi…

OBJECTIVE: To describe perioperative management and perinatal outcome for patients undergoing laparoscopy during pregnancy. PATIENTS AND METHODS: We conducted a retrospective study of all cases of laparoscopy during pregnancy performed in …

OBJECTIVE: With a prospective study, to evaluate the existence of two distinct clinical diseases in the endometriosis syndrome, by comparing pain symptoms and quality of life from patients with minimal endometriosis (AFS-R<5) and data from …

Journal de Gynecologie Obstetrique et Biologie de la Reproduction - Vol. 36 - N° 2 - p. 151-161

BACKGROUND: Deep infiltrating endometriosis (DIE) is commonly associated with severe pain. The pain can be managed successfully with GnRH agonists or continuous progestins. The precise molecular mechanism by which DIE causes pain or why hor…

From the literature, the crucial knowledge were drawn among endometriosis related infertility. Endometriosis is an important factor of infertility in minimal or light stages and a major one in mild or moderate stages. Thus, a laparoscopy mu…

Although malignant degeneration of cutaneous endometriosis is rare at only 0.3-1% in endometriosis surgical scars, diagnosis and management need to be defined. A case of malignant degeneration of perineal endometriosis is reported, with a r…

Endometriosis has long been considered as a disease of women over 30 years old. However, recent data from the literature demonstrated its high incidence in teenagers. Endometriosis in teenagers is generally associated with chronic pelvic pa…

Our recent DNA microarray analysis using tissue obtained by laser capture microdissection (LCM) identified up-regulation of RON (a tyrosine kinase receptor) during the late secretory phase in eutopic endometrial epithelial cells from patien…