Patricia L. Judson

The malignant transformation of normal cells is caused in part by aberrant gene expression disrupting the regulation of cell proliferation, apoptosis, senescence and DNA repair. Evidence suggests that the Bcl-2 antagonist of cell death (BAD…

In Brief Background: Endometriosis is a common disease of unclear etiology found in women of reproductive age. Symptoms of endometriosis usually resolve in the absence of normal ovarian function but have been reported to recur in the presen…

OBJECTIVE: Malignant transformation of endometriosis has been well documented. Endometrioid adenocarcinoma is the most common malignancy to occur in this setting, although other carcinomas and rarely stromal tumors can be seen. We present t…