OBJECTIVE: To evaluate deep nodular endometriotic lesions induced in baboons over 12 months and analyze collective cell migration and nerve fiber density. DESIGN: Morphologic and immunohistochemical analysis of endometriotic lesions induce…
OBJECTIVE: To determine the implications of collective cell migration in the invasion phenomenon observed in deep endometriotic lesions induced in a baboon model. DESIGN: Study of morphology and collective cell migration markers in invasiv…
OBJECTIVE: To evaluate, in peritoneal, ovarian, and rectovaginal endometriotic lesions, expression of steroidogenic enzymes involved in the activation and inactivation of estrogens: 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1) and 2 (H…
Objective Detection of nerve fibers in endometrial biopsies was recently proposed as a noninvasive diagnostic tool for endometriosis. However, their occurrence in the functional layer of endometrium still remains controversial. Nerve fibers…
OBJECTIVE: To establish an experimental model for the study of deep nodular endometriosis. DESIGN: Induction of nodular endometriosis in baboons by grafting different uterine specimens to the peritoneal cavity. SETTING: Research and unive…