E. Kubista

No ORCID on file · 8 papers in corpus
article 2010
Administration of βHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2010.01.010

Preliminary studies have shown that systemic beta-human chorionic gonadotrophin (betaHCG) therapy alleviates endometriosis-related chronic pelvic pain. The underlying mechanism, however, is completely unknown. This study has investigated th…

article 2007
Aromatase und Östrogen-Sulfotransferase (EST) Expression bei Endometriosepatientinnen – Hinweis für unbalancierte und autonome Östrogenproduktion in Endometrioseherden
·doi:10.1055/s-2007-983622

Endometriose ist eine hormonabhängige Erkrankung deren Entstehung und Fortschreiten mit einer gestörten Regulation der Östrogenproduktion verbunden ist. In diesem Zusammenhang stellen die Östrogen-bildende Aromatase und die Östrogen-abbauen…

article 2007
Expression of Aromatase and Estrogen Sulfotransferase in Eutopic and Ectopic Endometrium: Evidence for Unbalanced Estradiol Production in Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719107309120

Endometriosis is an estrogen-dependent gynecological disease causing pelvic pain and infertility. Impaired estrogen metabolism is thought to play a pivotal role in the pathogenesis of the disease. While there is some information on factors …

article 2005
Estrogen receptor β and matrix metalloproteinase 1 are coexpressed in uterine endometrium and endometriotic lesions of patients with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.06.014

ObjectiveTo evaluate the local matrix metalloproteinase 1 (MMP-1), estrogen receptor (ER) alpha, and ERbeta protein expression in eutopic and dystopic tissue from patients with endometriosis and to compare the endometrial expression pattern…

article 2005
Expressionsmuster von Östrogenrezeptor alpha, beta und Matrix-Metalloproteinase 1 – Hinweis für Östrogenrezeptor-beta mediiertes Wachstum von Endometrioseherden
·doi:10.1055/s-2005-920976

Fragestellung: Die Endometriose stellt neben Malignomen des weiblichen Genitale die häufigste Ursache für organdestruktives Wachstum im kleinen Becken dar, wodurch sich klassische Symptome wie Dypareunie, Dysmenorrhoe, Dysdefäkation oder Dy…

other 2005
Interleukin 1alpha and tissue-lytic matrix metalloproteinase-1 are elevated in ectopic endometrium of patients with endometriosis
Human Reproduction ·doi:10.1093/humrep/deh794

BACKGROUND: Matrix metalloproteinases (MMP) play an essential role in tissue remodelling and menstruation and appear to be regulated by cytokines such as interleukin-1alpha (IL-1alpha). In order to investigate their role in the pathogenesis…

article 2005
Verstärkte Expression von extrazellulärer-Matrix-auflösender Metalloproteinase-1 (MMP-1) und Interleukin 1α in Endometrioseherden
·doi:10.1055/s-2005-920973

Fragestellung: Die Endometriose stellt neben Malignomen des weiblichen Genitale die häufigste Ursache für organdestruktives Wachstum im kleinen Becken dar, wodurch sich klassische Symptome wie Dypareunie, Dysmenorrhoe, Dysdefäkation oder Dy…

article 1990
[Diagnosis and therapy of fibrocystic breast disease].

Fibrocystic disease (F.D.) can be observed in many women between 25 and 50 years. The typical histologic alterations in F.D. are often accompanied by estrogen dominance and relative hyperprolactinemia. For treatment local methods, diet, pro…