Kazuto Takayama

No ORCID on file · 7 papers in corpus
article 2013

In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu) 2cAMP or PGE 2 to give rise to physiologically significant estrogen biosynthesis. Since eut…

article 2013

C19 steroids are converted to estrogens by aromatase P450 (P450arom). Aromatase expression in humans is regulated by use of tissue-specific promoters in the placenta (promoter I.1), adipose tissue (promoters I.4, I.3, and II), and gonads (p…

review 2000
Trends in endocrinology and metabolism: TEM ·doi:10.1016/s1043-2760(99)00216-7

In contrast to normal endometrium, the expression of aromatase is aberrant in endometriosis and is stimulated by prostaglandin E2 (PGE2). This results in local production of estrogen, which induces PGE2 formation and establishes a positive …

article 1999
Molecular Endocrinology ·doi:10.1210/mend.13.2.0229

In stromal cells of endometriosis, marked levels of aromatase P450 (P450arom) mRNA and activity are present and can be vigorously stimulated by (Bu)2cAMP or PGE2 to give rise to physiologically significant estrogen biosynthesis. Since eutop…

article 1998
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.83.12.5301

Aberrant aromatase expression in stromal cells of endometriosis gives rise to conversion of circulating androstenedione to estrone in this tissue, whereas aromatase expression is absent in the eutopic endometrium. In this study, we initiall…

article 1998
Fertility and sterility ·doi:10.1016/s0015-0282(98)00022-3

ObjectiveTo treat an unusually aggressive case of recurrent postmenopausal endometriosis.DesignCase report.SettingUniversity of Texas Southwestern Medical Center (Dallas, Texas).Patient(s)A 57-year-old woman who presented with recurrent sev…

article 1997
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.82.2.3783

C19 steroids are converted to estrogens by aromatase P450 (P450arom). Aromatase expression in humans is regulated by use of tissue-specific promoters in the placenta (promoter I.1), adipose tissue (promoters I.4, I.3, and II), and gonads (p…