Mark D. Hornstein

OBJECTIVE: To assess whether add-back therapy with norethindrone acetate or norethindrone acetate plus conjugated equine estrogens is superior to maintain bone health in adolescents and young women using gonadotropin-releasing hormone agoni…

OBJECTIVE: To compare on a population basis the birth outcomes of women treated with assisted reproductive technologies (ART), women with indicators of subfertility but without ART, and fertile women. DESIGN: Longitudinal cohort study. SE…

ABSTRACT Endometriosis affects 10–15 % of women and is associated with pelvic pain and infertility. Angio-genesis plays an essential role in its pathogenesis. Den-dritic cells (DCs) were recently implicated in supporting tumor angiogenesis.…

OBJECTIVE: To identify a group of deliveries to mothers with indicators of subfertility (SUBFERTILITY). DESIGN: Longitudinal cohort study. SETTING: Hospital. PATIENT(S): A total of 334,152 deliveries to Massachusetts mothers in a Massach…

PURPOSE: To assess how patients perceive various lifestyle behaviors impact IVF success. METHODS: Cross-sectional study of heterosexual, English-speaking couples (n = 138) who completed web-based surveys during IVF treatment cycle. Perceiv…

Endometriosis is a common condition associated with pelvic pain and infertility. This study group has previously shown that supplementation of dendritic cells led to enhancement of endometriosis lesion growth and angiogenesis. This study de…

PURPOSE: To compare ages of mothers and of fathers at delivery in couples who are fertile, subfertile, and subfertile treated with assisted reproductive technology (ART) and to characterize birth outcomes in the ART population according to …

PURPOSE: To determine embryo and cycle-specific parameters associated with twin live birth in day 3 cryopreserved double embryo transfer (DET) cycles, and to propose a new prediction model for external validation. METHODS: All cycles with …

OBJECTIVE: To compare the efficacy of leuprolide and continuous oral contraceptives in the treatment of endometriosis-associated pain. DESIGN: Prospective, randomized, double-blind controlled trial. SETTING: Academic medical centers in Ro…

BACKGROUND: Endometriosis is a prevalent but enigmatic gynecologic disorder for which few modifiable risk factors have been identified. Fish oil consumption has been associated with symptom improvement in studies of women with primary dysme…

OBJECTIVE: To compare patterns of luteal phase bleeding (LPB) in IVF cycles supplemented with Crinone and with intramuscular progesterone (IMP) and to evaluate the impact of luteal estrogen supplementation on LPB. DESIGN: Prospective, rand…

OBJECTIVE: To evaluate ethnic differences in assisted reproductive technology (ART) outcomes in the United States. DESIGN: Historical cohort study. SETTING: Clinic-based data. PATIENT(S): A total of 139,027 ART cycles from the Society fo…

the conclusion that women with a high fatty acid intake are less likely to undergo a laparoscopy since a high fatty acid intake can reduce menstrual pain. Finally, laparoscopy as a diagnostic tool will pick up also subtle endometriosis and …

BACKGROUND: In the one study examining the relationship, adolescent physical activity was not associated with risk for endometriosis. Case-control studies have shown 40-80% reductions in risk for adult activity, while only an 11% reduction …

BACKGROUND: Regular exercise has been associated with a 40%-80% reduction in risk for endometriosis in several case-control studies. However, women experiencing symptoms prior to their diagnosis may be less likely to exercise than healthy c…

OBJECTIVE: To address the lack of predictors of IVF success by using proteomic biometrics. DESIGN: Experimental study of follicular fluid specimens from a prospective cohort of IVF patients. SETTING: Academic research laboratory and IVF p…

Endometriosis affects 10-15% of women and is associated with pelvic pain and infertility. Angiogenesis plays an essential role in its pathogenesis. Dendritic cells (DCs) were recently implicated in supporting tumor angiogenesis. As both tum…

Clinicians may wish to use the T-ACE, a screening instrument for prenatal risk drinking, for their infertile patients. Twenty-eight T-ACE negative and 23 T-ACE positive women presenting to an academic infertility clinic completed two interv…

Endometriosis is defined as the presence of endometrial glands and stroma outside the uterine cavity. It is typically confined to the pelvis, particularly the ovaries, posterior cul-desac, anterior uterovesical peritoneum, uterosacral ligam…

OBJECTIVE: To investigate differences in characteristics of patients with endometriosis in the United States and the United Kingdom. DESIGN: Patient questionnaire. SETTING: Two university-based endometriosis referral centers. PATIENT(S):…