Michele Vignali

No ORCID on file · 40 papers in corpus
case-report 2015
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2015.01.021

A panel of experts in the field of endometriosis expressed their opinions on management options in a 35-year-old patient desiring pregnancy with a history of previous surgery for endometrioma and bowel obstruction symptoms. Many questions t…

nonrandomized-trial 2015
Journal of Obstetrics and Gynaecology Research ·doi:10.1111/jog.12830

AIM: The long-term effects of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral ovarian endometriomas were evaluated. METHODS: A total of 22 patients undergoing laparoscopic cystectomy for unilateral endo…

other 2011
Human Reproduction ·doi:10.1093/humrep/der270

BACKGROUND: Pelvic inflammatory phenomena have been suggested as critical players in the natural history of endometriosis. However, to what extent these events could affect the systemic immunologic status remains to be clarified. Here, we c…

nonrandomized-trial 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.02.034

OBJECTIVE: To evaluate whether the amount of ovarian tissue inadvertently removed along with the endometrioma cyst wall at laparoscopy differs in relation to the operating surgeon's level of expertise. DESIGN: Multicenter, prospective tria…

other 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.10.014

OBJECTIVE: To evaluate differences in endometrial stromal cell (ESC) migration between patients with and without endometriosis. DESIGN: Differences in ESC migration, cellular morphology, and cytoskeletal-actin dynamics were evaluated in re…

other 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2009.12.018

The aim of the present study was to investigate whether alterations of the P receptor-A/P receptor-B ratio could be considered an etiopathogenetic factor for endometriosis. We failed to observe statistically significant differences in both …

review 2009
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2008.12.013

Endometrioma is one of the most frequent pathologies in gynecologic surgery. Laparoscopic cyst excision is considered the best treatment in terms of lower recurrence and improved fertility. However, it was recently questioned whether the ex…

review 2007
Frontiers in Bioscience ·doi:10.2741/2308

Family and twin studies have shown that heritability accounts for endometriosis development to an extent similar to other complex genetic diseases. Both linkage analysis and association studies have been performed to identify genetic determ…

other 2007
Human Reproduction ·doi:10.1093/humrep/dem341

BACKGROUND: Vascular endothelial growth factor (VEGF) is a potent stimulus of angiogenesis potentially contributing to the pathogenesis of endometriosis. The aim of this study was to investigate the potential association between the single …

observational 2006
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2006.01.078

OBJECTIVE: This study was undertaken to analyze the frequency and the determinants of long-term clinically detectable recurrence rate of deep, ovarian, and pelvic endometriosis. STUDY DESIGN: The clinical data of 1106 women with first diag…

observational 2006
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2006.03.064

OBJECTIVE: This study was undertaken to determine the frequency of postsurgical ovarian failure in patients undergoing laparoscopic excision of bilateral endometriomas. STUDY DESIGN: Patients who had been operated on for bilateral ovarian …

nonrandomized-trial 2005
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2005.06.006

STUDY OBJECTIVE: To evaluate damage to ovarian reserve following laparoscopic cystectomy of benign ovarian cysts. DESIGN: Prospective study (Canadian Task Force classification II-3). SETTING: Tertiary gynecologic endoscopic unit at a univ…

observational 2005
Journal of Minimally Invasive Gynecology ·doi:10.1016/j.jmig.2005.06.016

STUDY OBJECTIVE: To evaluate the risk of recurrence of deep endometriosis after conservative surgery. DESIGN: Retrospective analysis (Canadian Task Force classification II-3). SETTING: Tertiary care university hospital. PATIENTS: One hun…

observational 2003
Human Reproduction ·doi:10.1093/humrep/deg513

BACKGROUND: It has been suggested recently that deep endometriosis and the other forms of the disease do not share a common pathogenetic mechanism. In this study, we hypothesize that, if this is true, deep peritoneal endometriosis and the o…

review 2003
Current opinion in obstetrics & gynecology ·doi:10.1097/01.gco.0000084247.09900.4f

PURPOSE OF REVIEW: This review analyzes the literature on ovarian endometrioma, examining the controversies on pathogenesis, malignant transformation and surgical therapy. RECENT FINDINGS: Recent literature reflects the necessity of clearl…