Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts

NCT07686783 · ctgov recruiting

Enrollment: 60
Start: 2026-06-30
Completion: 2027-09-01
Last updated: 2026-07-07
Has results: False
Countries: Egypt

Conditions

Ovarian CystsEndometriosisBenign Ovarian CystOvarian ReserveCystectomy

Tagged with

endometriosis

Interventions

Laparoscopic Ovarian Cystectomy PROCEDURE
Laparoscopic excision of ovarian cyst under general anesthesia. The procedure includes: (1) CO₂ pneumoperitoneum creation via Veress needle through a 1-cm umbilical incision until intraabdominal pressure reaches 15 mmHg; (2) insertion of a 10-mm umbilical trocar and telescope; (3) placement of two or more 5-mm ancillary trocars under direct visualization; (4) incision of the ovarian capsule using monopolar scissors; (5) identification and careful dissection of the cyst wall from adjacent ovarian tissue using traction with grasping forceps; (6) hemostasis achieved using electrocoagulation or sutures; (7) plication and approximation of the ovarian incision edges; (8) for endometriosis cases, excision or cauterization of visible endometriotic lesions; (9) histopathological examination of the excised specimen to confirm diagnosis. The procedure is performed in both arms (endometriotic and non-endometriotic cysts) using identical surgical techniques.

Eligibility criteria

Inclusion Criteria: * Female patients aged 18-45 years * Ovarian cyst measuring 6-15 cm in diameter, confirmed by transvaginal ultrasound or MRI * Cyst is persistent for more than 3 months if asymptomatic, OR any symptomatic cyst regardless of duration of diagnosis * Serum anti-Müllerian hormone (AMH) level ≥ 2 ng/mL, measured within 1 month preoperatively * Willingness to participate and provide written informed consent Exclusion Criteria: * Clinical or ultrasonic suspicion of ovarian malignancy * Ovarian cyst associated with pregnancy * Previous history of ovarian surgery * History of pelvic irradiation or chemotherapy * Known endocrine disorders affecting ovarian function (e.g., PCOS, premature ovarian insufficiency, thyroid dysfunction, hyperprolactinemia) * Current use of hormonal contraceptives or hormonal therapy within 3 months prior to enrollment * Presence of severe systemic disease that contraindicates surgery or general anesthesia * Refusal to participate or inability to provide informed consent

License: public-domain-us · commercial use OK · attribution required
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine