Assessment of Ovarian Reserve in the Treatment of Ovarian Endometrioma With Cystectomy or Argon Plasma Coagulation: A Aandomized Clinical Trial
NCT07666412
· ctgov
not_yet_recruiting
- Enrollment
- 146
- Start
- 2026-06-08
- Completion
- 2029-12-08
- Last updated
- 2026-06-24
- Has results
- False
- Countries
- Italy
Conditions
Tagged with
Interventions
-
Argon Plasma Coagulation (APC) ablation
PROCEDURE
Cyst opening and drainage, ablation of the inner surface of the cyst capsule using APC, and multiple biopsies of the cyst capsule.
Eligibility criteria
Inclusion Criteria:
* Symptomatic patients (pain and/or infertility) affected by ovarian endometriomas (unilateral or bilateral).
* Age between 18 and 40 years.
* Ultrasound diagnosis of one or more mono- or bilateral endometriotic cysts, with a maximum overall diameter (per ovary) ≤ 80 mm and at least one cyst diameter ≥ 20 mm.
* Use of hormonal therapy for at least 1 month prior to surgery.
* Willingness to undergo follow-up at 40-60 days and 12 months, according to clinical practice.
* Willingness to receive postoperative hormonal therapy, according to clinical practice, to minimize the risk of recurrence.
* Written informed consent obtained.
Exclusion Criteria:
* History of unilateral ovariectomy/adnexectomy or hysterectomy.
* Ultrasound evidence of other non-endometriotic ovarian cysts requiring surgical removal.
* Atypical endometrioma or ultrasound suspicion of malignancy.
* Previous surgery on one or both ovaries within 12 months prior to surgery.
* Known or suspected active oncological disease.
* Inability to undergo transvaginal ultrasound examination (patients with intact hymen).
License: public-domain-us
· commercial use OK
· attribution required
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine