Interaction Between Decidual Cells and NK Cells in Endometriosis
NCT07652593
· ctgov
not_yet_recruiting
- Enrollment
- 50
- Start
- 2026-06-01
- Completion
- 2027-10-01
- Last updated
- 2026-06-17
- Has results
- False
- Countries
- France
Conditions
Tagged with
Interventions
-
Biological Sample Collection
PROCEDURE
Collection of blood samples, endometrial samples, vaginal microbiota samples, and surgical specimens when clinically indicated for immunological and biomarker analyses.
Eligibility criteria
Inclusion Criteria:
* Endometriosis Group
* Female participant aged 18 years or older.
* Confirmed diagnosis of deep endometriosis by imaging or surgery.
* Pelvic pain and/or severe dysmenorrhea (Visual Analog Scale \> 4).
* Premenopausal.
* No contraceptive or hormonal treatment during the study menstrual cycle.
* Affiliated with a health insurance system.
* Able and willing to provide written informed consent.
* Control Group
* Female participant aged 18 years or older.
* No diagnosis of endometriosis.
* Premenopausal.
* No contraceptive or hormonal treatment during the study menstrual cycle.
* No chronic pelvic pain or severe dysmenorrhea (Visual Analog Scale \< 4).
* Affiliated with a health insurance system.
* Able and willing to provide written informed consent.
Exclusion Criteria:
* Current infection.
* Active cancer.
* Active autoimmune disease.
* Concomitant hormonal treatment.
* Pregnancy.
* Participant under guardianship or legal protection.
* Participant deprived of liberty.
License: public-domain-us
· commercial use OK
· attribution required
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine