Pilot Study to Characterize the Endometriosis Steroidome and Its Link to Endocrine Disruptors and Vaginal Dysbiosis
NCT06820450
· ctgov
recruiting
- Enrollment
- 135
- Start
- 2025-07-01
- Completion
- 2027-07-01
- Last updated
- 2026-06-24
- Has results
- False
- Countries
- France
Conditions
Tagged with
Interventions
-
Blood test
OTHER
A blood test (2 x 5 ml dry tubes) will be taken to analyze steroid profiles
-
urine sample
OTHER
a 20 ml urine sample will be taken to analyze steroid profiles
-
vaginal sample
OTHER
to characterize the microbiota.
Eligibility criteria
Inclusion Criteria:
* Women aged 18 to 45
* Free, informed and written consent from the patient to participate in the study
* Good understanding of the French language
* Patient affiliated to or benefiting from a social security or similar scheme
Specific inclusion criteria for each group:
Group 1. Controls.
* Women with no laparoscopically confirmed signs suggestive of deep endometriosis.
* No clinico-biological criteria in favour of a diagnosis of endometriotic disease, nor any radiological signs (ultrasound or MRI) suggestive of endometriosis.
Group 2. Cases of deep endometriosis.
* Newly diagnosed women (less than 12 months).
* Severe, deep endometriotic pathology with surgical indication (clinical examination, imaging tests, pre-operative findings).
Exclusion Criteria:
* Intercurrent diagnosis of pregnancy.
* Presence of other hormone-dependent pathologies (e.g. breast cancer, PCOS).
* Acute infection.
License: public-domain-us
· commercial use OK
· attribution required
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine