Endometriosis Transcriptomic Cell Atlas
NCT06502548
· ctgov
recruiting
- Enrollment
- 92
- Start
- 2024-09-27
- Completion
- 2027-09-01
- Last updated
- 2026-11-05
- Has results
- False
- Countries
- France
Conditions
Tagged with
Interventions
-
Endometriosis
PROCEDURE
Anatomopathology waste will be recovered, i.e. the remainder of the endometriosis lesions and the remainder of the endometrial biopsy. A blood sample will be taken the day before surgery, as part of the treatment, for a hormonal check-up.
-
Tubal ligation or Hysterectomy
PROCEDURE
During surgery, an endometrial biopsy will be taken for research purposes. A blood sample will be taken the day before surgery, as part of the treatment, for a hormonal check-up.
Eligibility criteria
Inclusion Criteria:
* Patients over 18 and under 45 years of age
* Patients with multiple endometriosis sites (superficial, deep and endometriomas) with an indication for surgery to treat disabling painful symptoms and stage III or IV endometriosis in the context of infertility.
* Healthy patients including those operated on between the ages of 18 and 45 for tubal ligation
* Healthy patients operated on between the ages of 18 and 45 for hysterectomies for benign causes other than endometriosis or adenomyosis
* Patients operated on strictly at the time of menstruation
* Participants who have not been on hormonal treatment for 2 months
* Participant having signed the free and informed consent form
* Membership of a Social Security scheme or equivalent
Exclusion Criteria:
* Patients with endometriosis non-surgically treated
* Patients with endometriosis receiving hormonal treatment at the time of surgery or having received hormonal treatment in the 2 months prior to surgery
* Patients with adenomyosis only
* Healthy non-endometriotic patients undergoing hysterectomy for infectious or malignant causes
* Patients benefiting from a legal protection measure (guardianship, curatorship, safeguard of justice)
* Patients with positive serology for human immunodeficiency virus (HIV), human T-lymphotropic virus (HTLV), hepatitis B (HBV) and hepatitis C (HCV)
License: public-domain-us
· commercial use OK
· attribution required
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine
Courtesy of ClinicalTrials.gov / U.S. National Library of Medicine